(Christison & Ivany 2006) 自閉症とグルテン

日本ではそれほどではないが、海外ではグルテンやカゼインが自閉症の原因になると本気で思い込んでいる人が多いようだ。

小麦粉のグルテン
乳製品のカゼイン
この二つは過敏症を起こしやすく、子供では自閉症と診断された
ジム・キャリーの奥さん
彼女は自分の子供を治すために必死で方法を探し、グルテン・カゼイン除去療法で子供の自閉症を治してしまうのです！

著名人の影響というものは、日本でも海外でも絶大。困ったものだ。

J Dev Behav Pediatr. 2006 Apr;27(2 Suppl):S162-71.

Elimination diets in autism spectrum disorders: any wheat amidst the chaff?

Christison GW, Ivany K.
Department of Psychiatry, Loma Linda University School of Medicine, Loma Linda, California 92354, USA. gchristison@llu.edu
Abstract
The use of complementary or alternative treatment approaches in children with autism spectrum disorders (ASDs) is increasing, and the most popular of such approaches are diets that eliminate either gluten or casein, or both. The popularity of these diets indicates a need for more rigorous research into their efficacy. Owing to significant methodological flaws, the currently available data are inadequate to guide treatment recommendations. The purpose of this review is to examine the available trials of gluten/casein diets in children with ASDs regarding the strength of their findings and also concerning points that may be useful in the design of future studies. Seven trials of these diets in ASD are critically reviewed; 6 of these were uncontrolled trials and 1 used a single-blind design. All reported efficacy in reducing some autism symptoms, and 2 groups of investigators also reported improvement in nonverbal cognition. Design flaws in all of the studies weaken the confidence that can be placed in their findings. Careful double-blind, placebo-controlled studies are needed to evaluate whether actual benefit undergirds the diets' popularity and to provide better guidance to clinicians and caregivers. The literature currently available suggests that diets eliminating both gluten and casein (rather than either alone) should be studied first and that outcome measures should include assessments of nonverbal cognition.
PMID: 16685183 [PubMed - indexed for MEDLINE]
Elimination diets in autism spectrum disorders: any wheat amidst the chaff? - PubMed - NCBI

自閉症スペクトラム障害における除去食：籾殻に包まれた小麦？
自閉症スペクトラム障害児への補完的な、あるいは代替的な治療アプローチは増加しつつあり、そのようなアプローチのうち最も一般的なものはグルテンやカゼインを除いた食事である。現状では明確なエビデンスは存在しない。このような食事療法への人気は、それらの効果に関するより厳格な調査の必要性を示している。

ちなみに「chaff」には、「冷やかし」とか「バカ話」といった意味もあるので、おそらくそれにかけているのだろう。